OxymaPure
OxymaPure® used with DIC produces peptides with increased yield and decreased epimerization when used as an alternative to HOBt.1 This safe, non-explosive auxiliary nucleophile works with carbodiimide coupling strategies to provide the best results for a peptide synthesis. Additionally, the use of DIC/Oxyma avoids side reactions associated with high levels of base (≥ 1 equiv. DIEA) using onium salt methods such as HBTU/DIEA.
Standard Specifications
- Extremely fast acylation rates
- Non-explosive (compared to HOBt)
- Low cost
- Highly soluble in peptide synthesis solvents
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T.G. 2186
